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| Aberbinhery | Дата: Четверг, 12.09.2013, 09:02 | Сообщение # 1 |
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| It will take a concerted effort at all levels across our nation to empower all young people, especially young gay and bisexual youth, with the tools and resources they need to protect themselves from HIV infection, he urges. The CDC is in partnership with a number of organizations across and around the US to promote more HIV education and testing among young people. They are also funding the delivery of targeted testing and prevention for those at higher risk, and addressing the social and environmental issues that can put them at higher risk. In addition to this the CDC provides data and support to help communities and schools develop HIV and STD prevention programs. Written by Catharine Paddock PhD Researchers have found links between an individual's genetics and their response to treatment with chemotherapy. The findings, by researchers at the National Cancer Institute (NCI), part of the National Institutes of Health, and colleagues, show how a genetic variation, located in the SOD2 gene, may affect how a person responds to the chemotherapy drug cyclophosphamide. Cyclophosphamide is used in the treatment of breast and other cancers. The SOD2 gene produces a key protein that protects cells from damage by molecules known as reactive oxygen species, or free radicals. Reactive oxygen species are produced by normal cellular processes and the action of some chemotherapy drugs.
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The findings represent the first preliminary evidence pointing toward a mechanism and a potential biomarker for cyclophosphamide resistance in breast cancer patients. The study appeared online June 9, 2009, in Clinical Cancer Research. This study shows how, with the progress of individualized medicine, a diagnostic test may be developed that determines whether a patient has certain genetic variations that may modify the effect of certain chemotherapies, said study author Sharon Glynn, Ph. In the future, such tests may be used to guide the treatment of patients with the SOD2 variation, ensuring that they receive a therapy that is more effective than cyclophosphamide-based therapies, added senior author Stefan Ambs, Ph. Most genes in human cells are present in two copies-one inherited from the mother and the other inherited from the father.
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